Akademik Bilgiler



NECİL KÜTÜKÇÜLER
PROFESÖR
Tıp Fakültesi
Dahili Tıp Bilimleri Bölümü
Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı
İletişim Bilgileri- E-posta: necil.kutukculer@ege.edu.tr
- Telefon: 3881858
Eğitim Bilgileri- Yüksek Lisans: Ege Üniversitesi Tıp fakültesi, Türkiye, 1983
- Yardımcı Doçentlik: Çocuk sağlığı ve Hastalıkları ABD, Türkiye, 1992
- Doçentlik: Çocuk Sağlığı ve Hastalıkları, Türkiye, 1994
- Doktora: Pediatrik İmmünoloji Yan Dal İhtisası, Türkiye, 1998
- Profesörlük: Ege Üniversitesi Tıp Fak. Çocuk Sağlığı ve Hast., Türkiye, 2000

İdari ve Akademik Görevleri (1 adet)- Pediatrik İmmünoloji Bilim Dalı Başkanlığı, 1993-
Uzmanlık Alanları- İmmünoloji (1010503)
- Çocuk Sağlığı ve Hastalıkları (1011200)
- Çocuk Sağlığı ve Hastalıkları (1011201)
İndekslerce Taranan Dergilerdeki Yayınları (48 adet)- Kütükçüler Necil, Yağcı RV, Aydoğdu S, Aksu G, Genç B. Chronic inflammatory bowel disease in a patient with common variable immunodeficiency.The Turkish Journal of Pediatrics 43: 88-90, 2001.
- Buduneli N, Baylas H, Aksu G, Kütükçüler Necil. Prepubertal periodontitis associated with chronic granulamatous disease. Journal of Clinical Periodontology 28:589-93, 2001.
- Buduneli N, Kütükçüler Necil, Aksu G, Atilla G.Evaluation of transforming growth facror beta-1 level in crevicular fluid of cyclosporin A-treated patients. Journal of Periodontology 72: 526-31, 2001.
- Aksu G, Tırpan C, Çavuşoğlu C, Soydan S, Altare F, Casanova JL, Kutukculer N. Mycobacterium fortuitum chelonea complex infection in a child with complete interleukin-12 receptor beta-1 deficiency. Pediatric Infectious Disease Journal 20: 551-3, 2001.
- Kurugöl Z, Özkınay F, vardar F, Karacaali S, Kütükçüler Necil, Deveci R. Gricelli syndrome: Report of a case and review of the literature. Pediatrics International 43:298-301, 2001.
- Tütüncüoğlu S, Kütükçüler N, Kepe L, Çoker C, Berdeli A, tekgül H. Proinflammatory cytokines, prostaglandins and zinc in febrile convulsions. Pediatrics International 43: 235-239, 2001.
- Emingil G, Darcan S, Keskinoğlu A, Kütükçüler N, Atilla G. Localized aggressive periodontitis in a patient with Type 1 Diabetes Mellitus. a case report. Journal of Periodontology 72:1265-70, 2001.
- Kantar M, Kültürsay N, Kütükçüler N, Akısu M, Çetingül N, Çağlayan S. Plasma concentrations of granulocyte-macrophage colony-stimulating factor and interleukin -6 in septic and healthy preterms. European Journal of Pediatrics 2000: 159: 157-158.
- Kütükçüler N, Akil T, Egemen A, Kurugol Z, Akşit S, Özmen D, Turgan N, Bayındır O, Çağlayan S. adequate immune response to tetanus toxoid and failure of vitamin A and E supplementation to enhance antibody response in healthy children. Vaccine 2000: 18(26)2979-2984.
- Buduneli N, Atilla G, Kütükçüler N. Evaluation of TGF-beta1 level in gingival crevicular fluid of cyclosporine A treated patients. Journal of Clinical Periodontology 27 (suppl 1), 328, 2000.
- Kütükçüler Necil, Aksu Güzide. Is there an association between autoimmune hemolytic anemia and ataxia-telangiectasia ? Autoimmunity 2000: 32:145-147.
- Kavaklı K, Nişli G, Kütükçüler N, Aydınok Y, Öztop S, Çetingül N. Long term prophylaxis and immune parameters in Haemophilia. Journal of Tropical Pediatrics 45: 122-123, 1999.
- Hüseyinov A, Kütükçüler Necil, Aydoğdu S, Çağlayan S, Çoker I, Gökşen D, Yağcı RV. Increased gastric production of platelet-activating factor, leukotriene B4 and tumor necrosis factor-alpha in children with Helicobacter pylori infection. Digestive Disease and Sciences 44: 675-678, 1999.
- Tekgül H, Tütüncüoğlu S, Kütükçüler N, Dizdarer G, Hüseyinov A. Lymphocyte subsets and inflammatory mediators in patients with subacute sclerosing panencephalitis. Journal of Child Neurology 14: 418-421, 1999.
- Yalaz M, Parlar A, Huseyinov A, Özyürek R, kütükçüler N. The effect of cytokines (TNF-alpha, IL-1) and PAF on lipid profile during systemic infection in children. Atherosclerosis 146 (suppl 1):S32-S33, 1999.
- Kütükçüler N, Kavaklı K, Çetingül N, Aydınok Y, Nişli G. Plasma interleukin-3 (IL-3) and IL-7 concentrations in children with homozygous beta-thalassemia. Experimental Hematology 27 (7): suppl 1: S105, 1999.
- Kütükçüler Necil, Tütüncüoğlu S, Yılmaz D, Akalın T, Kandiloğlu G. Subcutaneous granuloma annulare and IgA-IgG2 deficiency. Turkish Journal of Pediatrics 40: 279-282,1998
- Kütükçüler Necil, Çağlayan S. Plasma and synovial fluid soluble CD23 concentrations in children with juvenile chronic arthritis. Autoimmunity 27: 155-158, 1998.
- Atilla G, Kütükçüler N. Crevicular fluid interleukin-1 beta, tumor necrosis factor-alpha and interleukin-6 levels in renal transplant patients receiving cyclosporine A. Journal of Periodontology 69: 784-790, 1998.
- Kütükçüler Necil, Aydoğdu S, Çağlayan S, Yağcı RV. Salivary and gastric fluid secretory immunoglobulin A and free secretory component concentrations in children with Helicobacter pylori-positive gastritis. Journal of Tropical Pediatrics 44:178-180,1998.
- Kütükçüler Necil, Çağlayan S, Aydoğdu F. Study of pro-inflammatory (TNF-alpha, IL-1 alpha, IL-6) and T cell-derived (IL-2, IL-4) cytokines in plasma and synovial fluid of patients with juvenile chronic arthritis: Correlations with clinical and laboratory parameters. Clinical Rheumatology 17: 288-292, 1998.
- Tekgül H, Kütükçüler Necil, Çağlayan S, Tütüncüoğlu S. Pro-inflammatory cytokines, lymphocyte subsets and intravenous immunoglobulin therapy in Guillain-Barre syndrome. Turkish Journal of Pediatrics 40:357-363, 1998.
- Hüseyinov A, Kütükçüler N, Aydoğdu S, Yağcı RV. Increased gastric production of PAF, LTB4 and TNF-alpha in children with Helicobacter pylori infection. Journal of Pediatric Gastroenterology and Nutrition 27(4): 475, 1998.
- Kütükçüler Necil, Vergin C, kavaklı K, Çetingül N, Öztop S, Nişli G, Çağlayan S. Specific antibody response in children with thalassemia major. Pediatric Hematology and Oncology 14: 181-183, 1997.
- Kütükçüler Necil, Aydoğdu S, Göksen D, Çağlayan S, Yağcı RV. Increased mucosal inflammatory cytokines in children with Helicobacter pylori-associated gastritis. Acta Pediatrica 86: 928-931, 1997.
- Kütükçüler Necil, Çağlayan S. Tumor necrosis factor-alpha and interleukin-6 in stools of children with bacterial and viral gastroenteritis. Journal of Pediatric Gastroenterology and Nutrition 25: 556-557, 1997.
- Çetingül N, Kütükçüler Necil, Kantar M, Kavaklı K, Nişli G, Çağlayan S, Öztop S. Recombinant human granulocyte-macrophage colony-stimulating factor therapy and endogenous plasma GM-CSF, IL-3, IL-4 concentrations in pediatric patients with solid tumors. Turkish Journal of Pediatrics 39: 473-481, 1997.
- Kurugöl Z, Egemen A, Erensoy S, Bilgiç A, Kütükçüler Necil. İntradermal administration of hepatitis-B vaccine in infants and preschool children. Turkish Journal of Pediatrics 39: 483-489, 1997.
- Kütükçüler Necil, Vergin C, Çetingül N, Kavaklı K, Çağlayan S, Öztop S, Nişli G. Plasma IL-3 and IL-7 concentrations in children with homozygous beta-thalassemia. Journal of Tropical Pediatrics 43: 366-367, 1997.
- Vergin C, Kütükçüler Necil, Çetingül N, Nişşli G, Çağlayan S, Öztop S. Serum immunoglobulins, IgG subclasses, isohemagglutinins and complemet-3 levels in patients with Thalassemia major. Indian Journal of Pediatrics 64: 215-219, 1997.
- Kütükçüler Necil, Kutlu O, Nişli G, Öztop S, Çetingül N, Çağlayan S. Assessment of neutrophil chemotaxis and random migration in children with thalassemia major. Pediatric Hematology and Oncology 13: 239-245, 1996.
- Kütükçüler Necil, Kurugöl Z, Egemen A, Yenigün A, Vardar F. The effect of immunisation against tetanus during pregnancy for protective antibody titres and specific antibody responses of infants. Journal of Tropical Pediatrics 42: 308-309, 1996.
- Narin N, Kütükçüler Necil, Narin F, Keser G, Doğanavşargil E. Anticardiolipin antibodies in acute rheumatic fever and chronic rheumatic heart disease: Is there a significant association ? Clinical and Experimental Rheumatology 14: 567-569, 1996.
- Kütükçüler Necil, Yağcı RV. Our experience in Reye's syndrome. Journal of Pediatric Gastroenterology and Nutrition 23: 338-339, 1996.
- Kütükçüler Necil, Shenton BK, Clark K, Rigg KM, Forsythe JLR, Kirby JA, Proud G, Taylor RMR. Renal allograft rejection.The temporal relationship and predictive value of plasma TNF (alpha and beta) , IFN-gamma and soluble ICAM-1. Transplant International 8: 45-50, 1995.
- Kütükçüler Necil, Shenton BK, Clark K, Rigg KM, Forsythe JLR, Proud G, Taylor RMR. The value of post-tranplant monitoring of IL-2, IL-3, IL-4, IL-6, IL-8 and soluble CD23 in the plasma of renal allograft recipients. Transplantation 59: 333-340, 1995
- Kütükçüler Necil, Özdoğru E, Demir E, Tanaç R. Plasma interleukin-3 and interleukin-4 concentrations in Turkish asthmatic children. Archives of Diseases in Childhood 73: 378-379, 1995.
- Narin N, Kütükçüler Necil, Özyürek R, Bakiler AR, Parlar A, Arcasoy M. Lymphocyte subsets and plasma IL-1 alpha, IL-2, and TNF-alpha concentrations in acute rheumatic fever and chronic rheumatic heart diseases. Clinical Immunology and Immunopathology 77: 172-176, 1995
- Kütükçüler Necil, Narin N. Plasma interleukin-7 (IL-7) and IL-8 concentrations in acute rheumatic fever and chronic rheumatic heart disease. Scandinavian Journal of Rheumatology 24: 383-385, 1995.
- Kütükçüler N, Parlar A, Özyürek N, Narin N. A case of common variable immunodeficiency presented symptoms of juvenile rheumatoid arthritis on admission. Clinical and Experimental Rheumatology 13 (S12): S52, 1995.
- Kültürsay N, Köprübaşı F, Kütükçüler Necil. Video display terrminal-the risk pf Trisomy 18? Clinical Genetics 45: 270-271,1994.
- Mir S, Kütükçüler Necil, Kavaklı K. Major histocompatibility complex antigens in Turkish children with steroid responsive nephrotic syndrome. Pediatric Nephrology 8: 259-260, 1994.
- Mir S, Kütükçüler Necil, Kavaklı K. Major histocompatibility complex antigens and immune mechanisms in steroid responsive nephrotic syndrome. Acta Pediatrica Japonica 36: 662-665, 1994.
- Mir S, Kütükçüler Necil, Çoker M, Keskinoğlu A. Major histocompatibility complex antigens in Turkish children with Henoch-Schonlein purpura. Nephrology, Dialysis, Transplantation 9: 586-587, 1994.
- Kültürsay N, Kütükçüler Necil, Büyükgebiz B, Kleijer WJ. A case of maple syrup urine disease misdiagnosed as tetanus neonatorum on admission. Acta Pediatrica Japonica 36: 284-286, 1994.
- Mir S, Kütükçüler Necil, Cura A. Use of single voided urine samples to estimate quantitative proteinuria in children. Turkish Journal of Pediatrics 34: 219-225, 1992.
- Mir S, Cura A, Kütükçüler N, Kavaklı K. Immune and genetic disorders in the pathogenesis of steroid-responsive nephrotic syndrome. Kidney International 41 (5) : 1467, 1992.
- Kütükçüler N, Çoker M, Mir S, Cura A. The relationship between pathogenesis of Henoch-Schonlein vasculitis and immunogenetic disorders. Kidney International 41(5): 1468, 1992.

İndekslerce Taranmayan Dergilerdeki Yayınları (34 adet)- Kütükçüler Necil. The role of nitric oxide in allergic inflammation. Turkish Journal of Immunology 4: S 25-27, 1999.
- Hasan Tekgül, Berhan Genç, Necil Kütükçüler, Sarenur Tütüncüoğlu. Febril konvülsiyon geçiren çocuklarda serum immünglobulin D düzeyleri. Ege Pediatri Bülteni 6: 123-127, 1999.
- 1995 ÖNCESİNDE TÜRKÇE YAYINLANAN ARAŞTIRMALAR VE TÜRKÇE YAYINLANMIŞ TÜM OLGU SUNULARI VE DERLEMELER BU LİSTEYE EKLENMEMİŞTİR. 1999 SONU İTİBARI İLE TOPLAM YAYIN SAYISI 105'TİR.
- Kavaklı K, Nişli G, Polat A, Kütükçüler N, Aydınok Y, Öztop S, Çetingül N. İntensive factor replacement and immune parameters in Hemophilia. Turkish Journal of Haematology 15: 67-70, 1998.
- Tanaç R, Kütükçüler N, Özdoğru E, Demir E. IgG subclass deficiency in extrinsic childhood asthma. Turkish Journal of Medical Sciences 27: 47-50, 1997.
- Vergin C, Kütükçüler Necil, Kavaklı K, Çetingül N, Öztop S, Nişli G, Çağlayan S. Beta-thalassemia major : plasma cytokine (IL-3, IL-7) concentrations regulating immune response and erythropoesis. Turkish Journal of Haematology 14: 97-100, 1997.
- Kütükçüler Necil, Demir E, Tanaç R, Çağlayan S. Plasma soluble CD23 and interleukin-4 concentrations in atopic children with bronchial asthma. Turkish Journal of Medical Sciences 27: 369-370, 1997.
- Kütükçüler Necil, Vergin C, Çetingül N, Nişli G, Kurugöl Z, Öztop S, Çağlayan S. The assessment of cell-mediated immunity and plasma IL-2 concentrations in children with Beta-thalassemia major. Turkish Journal of Immunology 2: 11-16, 1997.
- Kütükçüler Necil, Çağlayan S, Parlar A. A case of common variable immunodeficiency presenting with symptoms of juvenile rheumatoid arthritis on admission. Turkish Journal of Medical Sciences 26: 313-314, 1996.
- Kütükçüler Necil, Kurugöl Z, Demir E, Aydoğdu S. Evaluation of clinical and immunological parameters in children with primary immunodeficiency treated with intravenous immunoglobulin. Medical Journal of Ege University 4 (3-4): 61-63, 1996.
- Aydoğdu S, Kütükçüler N, yağcı RV, Çağlayan S. Rotavirüs infeksiyonu ve klinik özellikleri . Ege Pediatri Bülteni 3(4): 233-236, 1996.
- 1996, Kütükçüler Necil, Aydoğdu F, Parlar A, Çağlayan S. Juvenil romatoid artrit: Hastalık aktivitesinin izleminde laboratuvar göstergeler ve sinozyal sıvıdaki hücreler. Ege Pediatri Bülteni 6(3): 123-127, 1999.
- Bakiler AR, Kütükçüler Necil, Dorak C, Özyürek R, Narin N, Kültürsay N, Parlar A, Arcasoy M. Echocardiographic abnormalities in Turkish infants of diabetic mothers. Turkish Journal of Medical Sciences 23: 135-139, 1995.
- Kültürsay N, Tansuğ N, Kütükçüler Necil, Tokbaş A, Kutlu O. Ceftazidime treatment in severe neonatal infections. Annals of Medical Sciences 4: 8-12, 1995.
- Kültürsay N, Kütükçüler Necil, Tansuğ N, Kutlu O. Etiology, treatment and prognosis of early and late (nosocomial) septicemia in neonatal intensive care unit. Annals of Medical Sciences 4: 1-7, 1995.
- Kütükçüler Necil, Kültürsay N, Tansuğ N, Cin A. High-dose intravenous immunoglobulin therapy for hyperbilirubinemia caused by Rh and ABO hemolytic disease. Medical Journal of Ege University 5: 29-32, 1995.
- Kurugöl Z, Kütükçüler Necil, Egemen A, Yenigün A. Serum tetanus antitoin response to accelerated immunisation with diphteria, tetanus, pertussis vaccine. Turkish Journal of Medical Sciences 25: 189-191, 1995.
- Tansuğ N, Kütükçüler N, Oral R, Aısü M, Kültürsay N. Yenidoğanlarda atrial natriüretik peptid düzeyleri. Pediatride Yönelişler 1(11): 169-172, 1995.
- Kurugöl Z, Kütükçüler Necil. Anne sütü ve mama ile beslenmenin hücresel ve humoral immün sistem işlevlerine etkisi. Çocuk Sağlığı ve Hastalıkları Dergisi 38: 321-329, 1995.
- Demir E, Kütükçüler Necil, Tanaç R, Özdoğru E, Çoker M. IgA eksikliği olan olgularda IgA1, IgA2 ve IgG subgrupları. Ege Pediatri Bülteni 2(3): 175-178, 1995.
- Mir S, Kütükçüler N, Çoker M, keskinoğlu A. Immune system abnormalities in Henoch-Schonlein Purpura. Turkish Journal of Medical Sciences 21: 257-260, 1994.
- Kültürsay N, Köprübaşı F, Kütükçüler N. What is your diagnosis ? Turkish Journal of Medical Sciences 20: 277-278, 1994.
- Kütükçüler N. News from recent literature: Renal allograft rejection: Examination of adhesion blockade by antilymphocyte antibody drugs+ contributing editor's comments. Turkish Journal of Medical Sciences 20: 53, 1994.
- Ktükçüler Necil. About immunologic studies on recurrent respiratory tract infections (letter). Turkish Journal of Medical Sciences 20 (2): 127-128, 1994.
- Kütükçüler N, Shenton BK, White M. The efficacy of flow cytometric mpnitoring of T cells, LFA-1 alpha and beta during ATG treatment in acute renal allograft rejection. Turkish Journal of Medical Sciences 18: 219-226, 1993.
- Kütükçüler Necil, Mir S, Shenton BK, Micheson A, Kütükçüler A. Detection of antiendothelial /monocyte antibodies in children with end-stage renal failure before transplantation. Dialysis, Transplantation and Burn 7: 9-13, 1993.
- Yağcı RV, Kütükçüler N, Yüce G, Öztop F, Özkınay C, Özgür T, Taneli B. Our experience in Reye's syndrome. Medical Journal of Ege University 3: 121-124, 1993.
- Tütüncüoğlu S, Sönmez F, Kütükçüler Necil, Demirtaş E, Özgür T, Yüce G. a case of Lafora Body disease. Medical Journal of Ege University 2: 261-263, 1992.
- Kütükçüler Necil, Kavaklı K, Aydınok Y, Kavas İ, Mir S. A study of HLA antigens in end stage renal failure. Medical Journal of Ege University 1(1): 22-24, 1991.
- Cura A, Mir S, Kütükçüler Necil, Aksu N, Keskinoğlu A. The etiology of progressive loss of renal function in childhood. Dialysis, Transplantation and Burn 6: 15-18, 1991.
- Kültürsay N, kütükçüler Necil,Köprübaşı F, Utkaner I, Meral A. Prophylactic immunoglobulin administration to prevent neonatal septicemia. Turkish Journal of İnfection 5: 222-228, 1991.
- Mir S, Kütükçüler N, Kavaklı K, Tekgül H, Cura A. A study of HLA-A-B-C and DR antigens in 630 cases resident in Western Turkey. Medical Journal of Ege University 1: 95-97, 1991.
- Tütüncüoğlu S, Aydınok Y, Kütükçüler Necil, Kuzu F, Payzın S, Özgür T. Clinical perspective in Kawasaki disease (report of two cases) Medical Journal of Ege University 1: 95-97, 1991.
- Mir S, Cura A, Kütükçüler Necil, Aydınok Y, Kabasakl C. The role of urea kinetic modeling in childhood chronic hemodialysis. Dialysis, Transplantation and Burn 5(2) : 4550, 1990.

Bilimsel Kuruluş Üyeliklerim (3 adet)- European Society for Immunodeficiencies
- Milli Pediatri Derneği İzmir Şubesi
- Türk İmmünoloji Derneği